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Research briefs

What the published evidence actually says

One brief per compound. Each one reads the primary literature, says how strong it is, and says plainly where it does not exist. We take no money from anyone who sells these compounds, which is why some of these briefs are unflattering.

Every brief opens free: the key findings, and five of the sources themselves, there to be opened and checked. Our grade for the human evidence, and the review that argues for it, are the member edition. Members are the only people paying us, and that is the whole point.

Retatrutide

Graded for members

Marketed for

Weight loss.

Read the free preview

BPC-157

Graded for members

Marketed for

Tendon, ligament, muscle and gut healing; injury recovery.

Read the free preview

TB-500

Graded for members

Marketed for

Tendon, ligament and muscle repair; injury recovery; flexibility.

Read the free preview

Ipamorelin and CJC-1295

Graded for members

Marketed for

Muscle gain, fat loss, injury recovery, deeper sleep, anti-aging, bone density, cognition.

Read the free preview

GHK-Cu

Graded for members

Marketed for

Skin aging and wrinkles, wound healing, hair growth, tissue repair.

Read the free preview

What is free and what is paid

Free, no card. The opening of every brief: the key findings, and five of the sources, there to be opened and checked. And the peptide tracker, where you keep your own record of what you took and when. You enter everything yourself. We never suggest an amount.

$5 a month, or $29 a year. Our grade for the human evidence on every compound, the full review on every brief, the gaps we found, the complete source list, and each new brief as it is published.

The findings and the sources sit on the free side deliberately. Every fact a brief rests on can be read and checked here for nothing. What a membership buys is our judgment on it: the grade, and the review that argues for the grade.

Nobody who sells peptides pays us anything, and nothing we earn changes what a brief says. Members are the only people who pay us.

See the membership

How to read these briefs

We grade human evidence, not promise. A compound can have hundreds of animal papers and still sit at “none”, because the grade answers one question: has a controlled trial in people measured the thing this compound is sold for. Mechanism is not outcome. A raised blood marker is not a benefit.

We do not print dose figures. Trials are described by how many dose levels they tested and where a result sat among them, never by amount. Not because the numbers are secret, but because printing them turns a study description into an instruction, and this publication does not give instructions.

Absence of evidence is reported as a finding. Every brief ends with a list of what we looked for and could not find. A trial that completed and was never published, or a product nobody has ever chemically analyzed, tells you something real.

Every reference is one you can open. Each is tagged with what kind of evidence it is, from a randomized controlled trial in humans down to a cell culture experiment, so a trial and a mouse study are never presented as the same thing.

We say who is telling you. Where a body of evidence comes from one laboratory, or from an author with a commercial interest, or from conference abstracts that were never peer reviewed, the brief says so, because that changes how much weight it carries.